Orgone energy is a hypothetical form of energy first proposed and promoted in the 1930s by psychoanalyst Wilhelm Reich. He saw orgone as a universal bioenergetic force lying behind and causing much, if not all, observable phenomena. Reich's followers, such as Charles R. Kelley, went so far as to claim that orgone was the creative substratum in all of nature, comparable to Mesmer's animal magnetism, the Odic force of Carl Reichenbach and Henri Bergson's élan vital. The U.S. Food and Drug Administration (FDA) obtained a federal injunction barring the interstate distribution of orgone-related materials, on the charge that Reich and his associates were making false and misleading claims. The judge's injunction specified that all accumulators rented or owned by Reich and his associates and all labeling referring to orgone energy were to be destroyed.

Orgone was closely associated with sexuality: Reich, following Freud, saw nascent sexuality as the primary energetic force of life. The term itself was chosen to share a root with the word orgasm, which both Reich and Freud took to be a fundamental expression of psychological health. This focus on sexuality, while acceptable in the clinical perspective of Viennese psychoanalytic circles, scandalized the conservative American public even as it appealed to countercultural figures like William S. Burroughs and Jack Kerouac.

Orgone is regarded by the National Center for Complementary and Alternative Medicine as a type of "putative energy", a model which some therapists use for clinical procedures but which is untestable or defies measurement. According to writer K. Isaacs, the idea of orgone has no practical application in medicine or science.